Differentiating between multiple runas account windows

Differentiating between multiple runas account windows

In past jobs I've used a lot of runas /user:.. in order to allow quick
access between multiple accounts while logged in as a primary account.
Both server side or and on workstations. We're looking at situations where
sometimes a user might have multiple copies of the same application open
under different multiple user contexts.
As such it would be extremely useful to have some kind of visual queue to
differentiate based on the launching user.
In the past I always would just change the CMD prompt background colors.
Here I need it for GUI applications. It looks like changes to the color
scheme on Windows 7 / 2008 r2 read from the currently logged in user, not
from that specific user's profile. That seems to invalidate my first
choice.
What are my options?
Note: I did think about asking this on SU not here.. Didn't think there
would be many cases of people running applications under half a dozen
different accounts from one active session.